Relating Prognosis in Chromophobe Renal Cell Carcinoma to the Chromophobe Tumor Grading System

Relating Prognosis in Chromophobe Renal Cell Carcinoma to the Chromophobe Tumor Grading System

PURPOSE The chromophobe subtype of renal cell carcinoma (chRCC) has generally been associated with a better prognosis than the clear cell type; however, debate continues as to absolute prognosis as well as the significance of certain prognostic variables. We investigated the significance of pathologic stage and a recently proposed chromophobe tumor grading (CTG) scheme in predicting chRCC outco...

Sarcomatoid Transrormation of Chromophobe Renal Cell Carcinoma

Renal cell carcinoma: Update on grading of chromophobe subtype

The image shows a chromophobe RCC that is a FNG 3 and the revised CTG 1 Impact of the new grading system on clinical outcome Several studies have shown the lack of prognostic utility of Fuhrman nuclear grade in chromophobe RCCs. Some even advocate not grading chromophobe RCCs due to the inaccuracy of the current FNG system in this tumor subtype. In fact, approximately 80% of all chromophobe RCC...

Sarcomatoid Chromophobe Renal Cell Carcinoma with Heterologous Component

Clear cellrenal cell carcinoma (RCC) is the most common malignant renal tumor in adults, while chromophobe RCC (CRCC) is the third most common. Any subtypes of RCC can undergo sarcomatoid differentiation, but heterologous differentiation in sarcomatoid area is very rare in RCC. Here a61-year male is presented with hematuria and palpable mass. Clinicoradiologically, RCC was considered and left r...

Eosinophilic variant of chromophobe renal cell carcinoma.

Chromophobe renal cell carcinoma is a distinct subtype of renal cell carcinoma that accounts for 5% of all renal tumors. This subtype is further subdivided into two variants, classic and eosinophilic, with the latter variant being less frequent. We report two cases of the eosinophilic variant of chromophobe renal cell carcinoma diagnosed at our institution between January 2008 and December 2012.